An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Background: Up to half of Western children and adolescents experience at least one type of
childhood adversity. Individuals with a history of childhood adversity have an increased risk …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Highlights•Enhanced threat processing is a mechanism linking child trauma to
psychopathology.•Information processing biases and altered emotional learning are key …

Background Childhood maltreatment is a potent predictor of poor mental health across the
life span. We argue that there is a need to improve the understanding of the mechanisms …

Early life stress–including experience of child maltreatment, neglect, separation from or loss
of a parent, and other forms of adversity–increases lifetime risk of mood, anxiety, and …

Early life stress (ELS), in the form of childhood maltreatment, abuse, or neglect, increases
the risk for psychiatric sequelae later in life. The neurobiology of response to early stress …

Exposure to childhood adversity is common and a powerful risk factor for many forms of
psychopathology. In this opinion piece, we argue for greater translation of knowledge about …

We describe an ecological approach to understanding the developing brain, with a focus on
the effects of poverty-related adversity on brain function. We articulate how combining …

Childhood adversity is associated with altered reward processing, but little is known about
whether this varies across distinct types of adversity. In a sample of 94 children (6–19 years) …