Heritable predisposition is an important cause of cancer in children and adolescents.
Although a large number of cancer predisposition genes and their associated syndromes …

▪ Abstract The heparan sulfate on the surface of all adherent cells modulates the actions of a
large number of extracellular ligands. Members of both cell surface heparan sulfate …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

BACKGROUND & AIMS:: Early detection of hepatocellular carcinoma (HCC) is critical for
successful treatment. However, the differential diagnosis between HCC and benign hepatic …

While abnormalities in head circumference in autism have been observed for decades, it is
only recently that scientists have begun to focus in on the developmental origins of such a …

The hedgehog (Hh) family comprises sonic hedgehog (Shh), Indian hedgehog (Ihh), and
desert hedgehog (Dhh), which are versatile signaling molecules involved in a wide …

Abstract Glypican-3 (GPC3) is a heparan sulfate proteoglycan that is bound to the cell
membrane by a glycosyl-phosphatidylinositol anchor. GPC3 is expressed by most …

With the global pandemic of hepatitis B and C infections, the incidence of Hepatocellular
carcinoma (HCC) is rapidly increasing world wide. We identified glypican-3 (GPC3), a novel …

Schematic diagram of glypicans. GAG, glycosaminoglycan chains; GPI,
glycosylphosphatidylinositol anchor. tion between dally and decapentaplegic (dpp). dpp …

Prostate-specific antigen (PSA) screening for prostate cancer remains controversial because
it increases overdiagnosis and overtreatment of clinically insignificant tumors. Accounting for …