Children born with a solitary functioning kidney (SFK) have an increased risk of
hypertension and kidney disease from early in adulthood. In response to a reduction in …

Chronic kidney disease (CKD) affects> 10% of the world population, with increasing
prevalence in middle age. The risk for CKD is dependent on the number of functioning …

Background Estimation of glomerular function is necessary to diagnose kidney diseases.
However, the study of glomeruli in the clinic is currently done indirectly through urine and …

Despite significant advances in renal physiology, the global prevalence of chronic kidney
disease (CKD) continues to increase. The emergence of multicellular organisms gave rise to …

Purpose To assess the feasibility of using dissolved hyperpolarized xenon‐129 (129Xe) MRI
to study renal physiology in humans at 3 T. Methods Using a flexible transceiver RF coil …

Glomeruli number and size are important for determining the pathogenesis of glomerular
disease, chronic kidney disease, and hypertension. Moreover, renal injury can occur in …

There is greater than tenfold variation in nephron number of the human kidney at birth.
Although low nephron number is a recognized risk factor for CKD, its determinants are …

A practical research method integrating data-driven machine learning with conventional
model-driven statistics is sought after in medicine. Although glomerular hypertrophy (or a …

Dietary vitamin D plays an important role in maintaining proper vision. Age-related macular
degeneration (AMD) is a complex eye disease with unknown pathogenesis. Studies on …

As the kidneys age, gradual changes in the structures and functions of mitochondria occur.
Dietary restriction (DR) can play a protective role in ageing-associated renal decline …