Introduction Converging evidence suggests that ketamine elicits antidepressant effects via
enhanced neuroplasticity precipitated by a surge of glutamate and modulation of GABA …

Proton (1 H) magnetic resonance spectroscopy provides a non-invasive and quantitative
measure of brain metabolites. Traumatic brain injury impacts cerebral metabolism and a …

Sex hormones affect the GABAergic and glutamatergic neurotransmitter system as
demonstrated in animal studies. However, human research has mostly been correlational in …

Neural plasticity is a complex process dependent on neurochemical underpinnings. Next to
the glutamatergic system which contributes to memory formation via long-term potentiation …

Impaired cognitive flexibility represents a widespread symptom in psychiatric disorders,
including major depressive disorder (MDD), a disease, characterized by an imbalance of …

Purpose Recently, a 3D‐concentric ring trajectory (CRT)‐based free induction decay (FID)‐
MRSI sequence was introduced for fast high‐resolution metabolic imaging at 7 T. This …

Robust Animal-Based Measures (ABMs) are fundamental in order to assess animal welfare,
however in semi-extensive sheep farming systems is not easy to collect ABMs without …

Transcranial direct current stimulation (tDCS) over prefrontal cortex (PFC) regions is
currently proposed as therapeutic intervention for major depression and other psychiatric …

Seasonal changes in neurotransmitter systems have been demonstrated in imaging studies
and are especially noticeable in diseased states such as seasonal affective disorder (SAD) …

GABA+ and Glx (glutamate and glutamine) are widely studied metabolites, yet the commonly
used magnetic resonance spectroscopy (MRS) techniques have significant limitations …