CD169+ macrophages are a unique type of macrophage subset that differ from M1 and M2
macrophages. CD169+ macrophages are present in multiple tissues and organs throughout …

CD169, also known as Siglec1 or Sialoadhesin (Sn), is a surface adhesion molecule on
human myeloid cells. Being part of the Siglec family, it acts as a receptor for sialylated …

Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a
significant cause of morbidity and mortality in all age groups. The recent finding that HuNoV …

The identification of a bacterial, viral, or even noninfectious cause is essential in the
management of febrile syndrome in the emergency department (ED), especially in epidemic …

Siglecs are sialic acid (Sia) recognizing immunoglobulin-like receptors expressed on the
surface of all the major leukocyte lineages in mammals. Siglecs recognize ubiquitous Sia …

A strong bias related to age is observed in COVID-19 patients with pediatric subjects
developing a milder disease than adults. We hypothesized that a specific SARS-CoV-2 …

Siglec-1, also known as Sialoadhesin (Sn) and CD169 is highly conserved among
vertebrates and with 17 immunoglobulin-like domains is Siglec-1 the largest member of the …

Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections,
particularly in young children and older adults. In this review, we aimed to comprehensively …

CD4+ T cells are crucial cellular source of type 2 cytokines and responsible for RSV-induced
asthma-like symptoms and asthma exacerbations. However, the mechanism for regulating …

Background Evaluation of type I interferons (IFNs) in inflammatory or autoimmune diseases
is challenging because of their rapid clearance in peripheral blood. The IFN gene …