miEAA 2023: updates, new functional microRNA sets and improved enrichment visualizations

E Aparicio-Puerta, P Hirsch, GP Schmartz… - Nucleic acids …, 2023 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs that play a critical role in regulating
diverse biological processes. Extracting functional insights from a list of miRNAs is …

[HTML][HTML] Lineage Plasticity and Stemness Phenotypes in Prostate Cancer: Harnessing the Power of Integrated “Omics” Approaches to Explore Measurable Metrics

S Logotheti, E Papadaki, V Zolota, C Logothetis… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer remains the most frequent cause of cancer morbidity, the
second most frequent cause of cancer mortality in men in the developed world and is an …

[HTML][HTML] Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction

J Barbazan, C Pérez-González… - Nature …, 2023 - nature.com
During tumor progression, cancer-associated fibroblasts (CAFs) accumulate in tumors and
produce an excessive extracellular matrix (ECM), forming a capsule that enwraps cancer …

Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to preserve blood–brain barrier integrity

A Cash, C de Jager, T Brickler… - Proceedings of the …, 2023 - National Acad Sciences
Neurobiological consequences of traumatic brain injury (TBI) result from a complex interplay
of secondary injury responses and sequela that mediates chronic disability. Endothelial cells …

[HTML][HTML] Differential diagnosis of systemic lupus erythematosus and Sjögren's syndrome using machine learning and multi-omics data

J Martorell-Marugán, M Chierici, G Jurman… - Computers in Biology …, 2023 - Elsevier
Systemic lupus erythematosus and primary Sjogren's syndrome are complex systemic
autoimmune diseases that are often misdiagnosed. In this article, we demonstrate the …

[HTML][HTML] The role of microRNAs in the gonocyte theory as target of malignancy: looking for potential diagnostic biomarkers

F García-Andrade, RM Vigueras-Villaseñor… - International Journal of …, 2022 - mdpi.com
Some pediatric patients with cryptorchidism preserve cells with gonocyte characteristics
beyond their differentiation period, which could support the theory of the gonocyte as a …

[HTML][HTML] Transcriptome and proteome analysis reveals the anti-cancer properties of Hypnea musciformis marine macroalga extract in liver and intestinal cancer cells

R Begolli, M Chatziangelou, M Samiotaki, A Goutas… - Human Genomics, 2023 - Springer
Background Marine seaweeds are considered as a rich source of health-promoting
compounds by the food and pharmaceutical industry. Hypnea musciformis is a marine red …

[HTML][HTML] Transcriptome responses of lactic acid bacteria isolated from kimchi under hydrogen peroxide exposure

M Lee, D Kim, EJ Choi, JH Song, JY Kang… - Food Research …, 2023 - Elsevier
In this study, five species of lactic acid bacteria (LAB) isolated from kimchi were analyzed in
terms of their potential antioxidant activity. Latilactobacillus curvatus WiKim38 …

[HTML][HTML] Potential role of the regulatory miR1119-MYC2 module in wheat (Triticum aestivum L.) drought tolerance

R Shamloo-Dashtpagerdi, AG Shahriari… - Frontiers in Plant …, 2023 - frontiersin.org
MicroRNA (miRNA)-target gene modules are essential components of plants' abiotic stress
signalling pathways Little is known about the drought-responsive miRNA-target modules in …

[HTML][HTML] Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques

JA Clain, H Rabezanahary, G Racine, S Boutrais… - JCI insight, 2023 - ncbi.nlm.nih.gov
Identifying immune cells and anatomical tissues that contribute to the establishment of viral
reservoirs is of central importance in HIV-1 cure research. Herein, we used rhesus …