[HTML][HTML] It is the time for quorum sensing inhibition as alternative strategy of antimicrobial therapy

NG Naga, DE El-Badan, KM Ghanem… - Cell Communication and …, 2023 - Springer
Multiple drug resistance poses a significant threat to public health worldwide, with a
substantial increase in morbidity and mortality rates. Consequently, searching for novel …

[HTML][HTML] Quorum quenching: a drug discovery approach against Pseudomonas aeruginosa

MA Rather, D Saha, S Bhuyan, AN Jha… - Microbiological …, 2022 - Elsevier
Pseudomonas aeruginosa, a ubiquitous opportunistic and nosocomial biofilm-forming
pathogen with complex, interconnected and hierarchical nature of QS systems (Las, Rhl …

Exploration of CviR-mediated quorum sensing inhibitors from Cladosporium spp. against Chromobacterium violaceum through computational studies

M Murali, F Ahmed, HG Gowtham, JO Aribisala… - Scientific Reports, 2023 - nature.com
An opportunistic human pathogenic bacterium, Chromobacterium violaceum resists the
potency of most antibiotics by exploiting the quorum sensing system within their community …

Biofilm-Associated Agr and Sar Quorum Sensing Systems of Staphylococcus aureus Are Inhibited by 3-Hydroxybenzoic Acid Derived from Illicium verum

PS Ganesh, K Veena, R Senthil, K Iswamy… - ACS …, 2022 - ACS Publications
Biofilm-producing Staphylococcus aureus (S. aureus) is less sensitive to conventional
antibiotics than free-living planktonic cells. Here, we evaluated the antibiofilm activity of …

[HTML][HTML] Bacterial biofilm inhibitors: An overview

VC Kalia, SKS Patel, JK Lee - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Bacteria that cause infectious diseases adopt biofilms as one of their most prevalent
lifestyles. Biofilms enable bacteria to tolerate environmental stress and evade antibacterial …

Computational and Biological Evaluation of β-Adrenoreceptor Blockers as Promising Bacterial Anti-Virulence Agents

AJ Almalki, TS Ibrahim, SS Elhady, WAH Hegazy… - Pharmaceuticals, 2022 - mdpi.com
Bacterial resistance to antibiotics is an increasing public health threat as it has the potential
to affect people at any stage of life, as well as veterinary. Various approaches have been …

Quorum Sensing Inhibitory and Quenching Activity of Bacillus cereus RC1 Extracts on Soft Rot-Causing Bacteria Lelliottia amnigena

R Kachhadia, C Kapadia, S Singh, K Gandhi… - ACS …, 2022 - ACS Publications
The quorum sensing (QS) system of bacteria helps them to communicate with each other in
a density-dependent manner and regulates pathogenicity. The concentrations of …

Actinomycin D: a novel Pseudomonasaeruginosa quorum sensing inhibitor from the endophyte Streptomycescyaneochromogenes RC1

YX Zeng, JS Liu, YJ Wang, S Tang, DY Wang… - World Journal of …, 2022 - Springer
The infections caused by Pseudomonas aeruginosa are difficult to treat due to its multidrug
resistance. A promising strategy for controlling P. aeruginosa infection is targeting the …

Insights into antibiofilm mechanisms of phytochemicals: Prospects in the food industry

AGMS Uddin Mahamud, S Nahar… - Critical reviews in …, 2024 - Taylor & Francis
The recalcitrance of microbial aggregation or biofilm in the food industry underpins the
emerging antimicrobial resistance among foodborne pathogens, exacerbating the …

Chromobacterium violaceum: a model for evaluating the anti-quorum sensing activities of plant substances

PD Dimitrova, T Damyanova… - Scientia …, 2023 - mdpi.com
In the new antibiotic era, the exponential increase in multiresistant bacterial strains has
become the main global health problem. Many researchers have focused their efforts on …