[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy
Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …
A mechanistic review of β-carotene, lutein, and zeaxanthin in eye health and disease
Carotenoids are natural lipid-soluble antioxidants abundantly found as colorful pigments in
fruits and vegetables. At least 600 carotenoids occur naturally, although about 20 of them …
fruits and vegetables. At least 600 carotenoids occur naturally, although about 20 of them …
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants
B Poljsak, D Šuput, I Milisav - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Free radical damage is linked to formation of many degenerative diseases, including cancer,
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …
Age-related macular degeneration preferred practice pattern®
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …
vision impairment in developed countries. The primary risk factors for the development of …
Supplemental vitamins and minerals for CVD prevention and treatment
The authors identified individual randomized controlled trials from previous meta-analyses
and additional searches, and then performed meta-analyses on cardiovascular disease …
and additional searches, and then performed meta-analyses on cardiovascular disease …
Dietary vitamin C in human health
M Granger, P Eck - Advances in food and nutrition research, 2018 - Elsevier
Vitamin C is essential to prevent scurvy in humans and is implicated in the primary
prevention of common and complex diseases such as coronary heart disease, stroke, and …
prevention of common and complex diseases such as coronary heart disease, stroke, and …
Cataract in the Adult Eye Preferred Practice Pattern®
KM Miller, TA Oetting, JP Tweeten, K Carter, BS Lee… - Ophthalmology, 2022 - Elsevier
Evidence-based update of the Cataract in the Adult Eye Preferred Practice Pattern®(PPP)
guidelines, describing the prevalence, risk factors, and natural history of cataract …
guidelines, describing the prevalence, risk factors, and natural history of cataract …
Vitamin C as an antioxidant: evaluation of its role in disease prevention
SJ Padayatty, A Katz, Y Wang, P Eck… - Journal of the …, 2003 - Taylor & Francis
Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this
property accounts for all its known functions. As an electron donor, vitamin C is a potent …
property accounts for all its known functions. As an electron donor, vitamin C is a potent …
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and …
Age-Related Eye Disease Study … - Archives of …, 2001 - jamanetwork.com
Background Observational and experimental data suggest that antioxidant and/or zinc
supplements may delay progression of age-related macular degeneration (AMD) and vision …
supplements may delay progression of age-related macular degeneration (AMD) and vision …