Ionizing radiation-induced immune and inflammatory reactions in the brain

K Lumniczky, T Szatmári, G Sáfrány - Frontiers in immunology, 2017 - frontiersin.org
Radiation-induced late brain injury consisting of vascular abnormalities, demyelination,
white matter necrosis, and cognitive impairment has been described in patients subjected to …

Volumetric modulated arc therapy (VMAT): a review of clinical outcomes—what is the clinical evidence for the most effective implementation?

SO Hunte, CH Clark, N Zyuzikov… - The British Journal of …, 2022 - academic.oup.com
Modern conformal radiation therapy using techniques such as modulation, image guidance
and motion management have changed the face of radiotherapy today offering superior …

A prospective phase II randomized trial of proton radiotherapy vs intensity-modulated radiotherapy for patients with newly diagnosed glioblastoma

PD Brown, C Chung, DD Liu, S McAvoy… - Neuro …, 2021 - academic.oup.com
Background To determine if proton radiotherapy (PT), compared to intensity-modulated
radiotherapy (IMRT), delayed time to cognitive failure in patients with newly diagnosed …

Cognitive impairment and morphological changes after radiation therapy in brain tumors: a review

J Jacob, T Durand, L Feuvret, JJ Mazeron… - Radiotherapy and …, 2018 - Elsevier
Life expectancy of patients treated for brain tumors has lengthened due to the therapeutic
improvements. Cognitive impairment has been described following brain radiotherapy, but …

Dosimetric comparison of proton radiation therapy, volumetric modulated arc therapy, and three-dimensional conformal radiotherapy based on intracranial tumor …

S Adeberg, SB Harrabi, N Bougatf, V Verma… - Cancers, 2018 - mdpi.com
(1) Background: Selecting patients that will benefit the most from proton radiotherapy (PRT)
is of major importance. This study sought to assess dose reductions to numerous organs-at …

Treatment of meningioma and glioma with protons and carbon ions

S Adeberg, SB Harrabi, V Verma, D Bernhardt… - Radiation …, 2017 - Springer
The rapid rise of particle therapy across the world necessitates evidence to justify its ever-
increasing utilization. This narrative review summarizes the current status of these …

Exosomal plasminogen activator inhibitor-1 induces ionizing radiation-adaptive glioblastoma cachexia

E Shin, H Kang, H Lee, S Lee, J Jeon, K Seong… - Cells, 2022 - mdpi.com
Cancer cachexia is a muscle-wasting syndrome that leads to a severely compromised
quality of life and increased mortality. A strong association between cachexia and poor …

Proton therapy and gliomas: a systematic review

I Chambrelant, J Eber, D Antoni, H Burckel, G Noël… - Radiation, 2021 - mdpi.com
Background: Gliomas are primary cerebral tumors. Radiation therapy plays a key role in
their treatment but with a risk of toxicity associated with the dose to and volume of normal …

Neurocognitive outcomes in pediatric patients following brain irradiation

K Weusthof, P Lüttich, S Regnery, L König, D Bernhardt… - Cancers, 2021 - mdpi.com
Simple Summary Since inception, radiation therapy in pediatric brain tumor patients has
been associated with neurocognitive decline and persistent impairment. Recently published …

Hippocampus-sparing radiotherapy using volumetric modulated arc therapy (VMAT) to the primary brain tumor: the result of dosimetric study and neurocognitive …

KS Kim, CW Wee, JY Seok, JW Hong, JB Chung… - Radiation …, 2018 - Springer
Background We hypothesized that hippocampal-sparing radiotherapy via volumetric
modulated arc therapy (VMAT) could preserve the neurocognitive function (NCF) of patients …