The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …

The complement cascade is an ancient immune‐surveillance system that not only provides
protection from pathogen invasion but has also evolved to participate in physiological …

The present invention relates to an immunogenic composi tion. More particularly, the
present invention is a composition directed to eliciting an immune response to at least one …

Complement-mediated synapse elimination has emerged as an important process in both
brain development and neurological diseases, but whether neurons express complement …

The complement system is a central component of innate immunity and bridges the innate to
the adaptive immune response. However, it can also turn its destructive capabilities against …

The metzincin metalloproteinase PAPP-A plays a key role in the regulation of insulin-like
growth factor (IGF) signaling by specific cleavage of inhibitory IGF binding proteins (IGFBPs) …

Complement is a central part of the immune system that has developed as a first defense
against non-self cells. Neoplastic transformation is accompanied by an increased capacity of …

Membranoproliferative glomerulonephritis type II (MPGN II) is a rare disease characterized
by the deposition of abnormal electron-dense material within the glomerular basement …

Complement in mammalian plasma recognizes pathogenic, immunogenic and apoptotic cell
surfaces, promotes inflammatory responses and marks particles for cell lysis, phagocytosis …

Over the last few years, dramatic increases in our knowledge about diffusely adhering
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …