Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

Millions of patients worldwide suffer from gastrointestinal (GI) motility disorders such as
gastroparesis. These disorders typically include debilitating symptoms, such as chronic …

Smooth muscle layers of the gastrointestinal tract consist of a heterogeneous population of
cells that include enteric neurons, several classes of interstitial cells of mesenchymal origin …

The term gastrointestinal neuromuscular disease describes a clinically heterogeneous
group of disorders of children and adults in which symptoms are presumed or proven to …

Background & Aims: Maintaining the integrity of networks of interstitial cells of Cajal (ICC) is
essential to preserve orderly contractile activity and neuroregulation in the gastrointestinal …

Gastroenteropathy causes considerable morbidity in patients with diabetes mellitus and
represents a major healthcare burden. Current treatments are largely symptomatic and …

Normal motility of the colon is critical for quality of life and efforts to normalize abnormal
colon function have had limited success. A better understanding of control systems of …

BACKGROUND & AIMS: Gastrointestinal stromal tumors (GIST) are related to interstitial cells
of Cajal (ICC) and often contain activating stem cell factor receptor (Kit) or platelet-derived …

Slow waves are known to originate orally in the stomach and to propagate toward the
antrum, but the exact location of the pacemaker and the precise pattern of propagation have …

Hesperidin is one of the main active ingredients of Citrus aurantium L.(Rutaceae) and
tangerine peel, which have anti-inflammatory and antioxidant effects. In previous study, we …