Peripheral nerve regeneration and muscle reinnervation

T Gordon - International journal of molecular sciences, 2020 - mdpi.com
Injured peripheral nerves but not central nerves have the capacity to regenerate and
reinnervate their target organs. After the two most severe peripheral nerve injuries of six …

Strategies to promote peripheral nerve regeneration: electrical stimulation and/or exercise

T Gordon, AW English - European Journal of Neuroscience, 2016 - Wiley Online Library
Enhancing the regeneration of axons is often considered to be a therapeutic target for
improving functional recovery after peripheral nerve injury. In this review, the evidence for …

Timing of surgical intervention in cauda equina syndrome: a systematic critical review

AMT Chau, LL Xu, NR Pelzer, C Gragnaniello - World neurosurgery, 2014 - Elsevier
Objective Cauda equina syndrome (CES) is a rare but important neurosurgical emergency.
Despite being a recognized clinical entity since 1934, there remains significant uncertainty …

Standards of care in cauda equina syndrome

NV Todd, RA Dickson - British journal of neurosurgery, 2016 - Taylor & Francis
What constitutes cauda equina syndrome (CES), how it should be subclassified and how
urgently to image and operate on patients with CES are all matters of debate. A structured …

Brief Electrical Stimulation Promotes Recovery after Surgical Repair of Injured Peripheral Nerves

T Gordon - International Journal of Molecular Sciences, 2024 - mdpi.com
Injured peripheral nerves regenerate their axons in contrast to those in the central nervous
system. Yet, functional recovery after surgical repair is often disappointing. The basis for …

Nerve regeneration: understanding biology and its influence on return of function after nerve transfers

T Gordon - Hand Clinics, 2016 - hand.theclinics.com
Poor functional outcomes are frequent after peripheral nerve injuries despite the
wellrecognized capacity for the Schwann cells (SCs) of the peripheral nervous system to …

[HTML][HTML] Delayed decompression for cauda equina syndrome secondary to lumbar disc herniation: long-term follow-up results

LAI Xunwei, LI Wei, W Jixing, H ZHANG… - Journal of Southern …, 2017 - ncbi.nlm.nih.gov
Objective To assess the impact of delayed decompression on long-term neurological and
bladder function recovery in patients with cauda equina syndrome (CES) secondary to …

Neurological deterioration in cauda equina syndrome is probably progressive and continuous. Implications for clinical management

NV Todd - British Journal of Neurosurgery, 2015 - Taylor & Francis
Fifty-six human and animal studies of cauda equina syndrome (CES) were reviewed. The
evidence from human studies was poor (level IV). Evidence from animal studies and limited …

Innervation and function of rat tail muscles for modeling cauda equina injury and repair

SJ MacKenzie, JL Yi, A Singla, TM Russell… - Muscle & …, 2015 - Wiley Online Library
Introduction: The rat tail exhibits functional impairment after cauda equina injury. Our goal
was to better understand the innervation and roles of muscles that control the tail. Methods …

Large animal models of human cauda equina injury and repair: evaluation of a novel goat model

W Chen, P Zhang, F Xue, X Yin, C Qi, J Ma… - Neural regeneration …, 2015 - journals.lww.com
Previous animal studies of cauda equina injury have primarily used rat models, which
display significant differences from humans. Furthermore, most studies have focused on …