Myocardial infarction from a tissue engineering and regenerative medicine point of view: A comprehensive review on models and treatments
In the modern world, myocardial infarction is one of the most common cardiovascular
diseases, which are responsible for around 18 million deaths every year or almost 32% of all …
diseases, which are responsible for around 18 million deaths every year or almost 32% of all …
Silk fibroin increases the elasticity of alginate-gelatin hydrogels and regulates cardiac cell contractile function in cardiac bioinks
Silk fibroin (SF) is a natural protein extracted from Bombyx mori silkworm thread. From its
common use in the textile industry, it emerged as a biomaterial with promising biochemical …
common use in the textile industry, it emerged as a biomaterial with promising biochemical …
[HTML][HTML] Three-Dimensional iPSC-Based In Vitro Cardiac Models for Biomedical and Pharmaceutical Research Applications
S Bufi, R Santoro - International Journal of Molecular Sciences, 2024 - mdpi.com
Cardiovascular diseases are a major cause of death worldwide. Advanced in vitro models
can be the key stone for a better understanding of the mechanisms at the basis of the …
can be the key stone for a better understanding of the mechanisms at the basis of the …
[HTML][HTML] 3D bioprinted alginate-gelatin hydrogel patches containing cardiac spheroids recover heart function in a mouse model of myocardial infarction
Epicardial transplantation of 3D bioprinted patches represents a promising protective
strategy against infarction-induced myocardial damage. We previously showed that 3D …
strategy against infarction-induced myocardial damage. We previously showed that 3D …
Fibulin-3 Deficiency Protects Against Myocardial Injury Following Ischaemia/ Reperfusion in in vitro Cardiac Spheroids
Myocardial infarction (MI, or heart attack) is a leading cause of death worldwide. Myocardial
ischaemia reperfusion (I/R) injury typical of MI events is also associated with the …
ischaemia reperfusion (I/R) injury typical of MI events is also associated with the …
Chlorella-enriched hydrogels protect against myocardial damage and reactive oxygen species production in an in vitro ischemia/reperfusion model using cardiac …
Microalgae have emerged as promising photosynthetic microorganisms for biofabricating
advanced tissue constructs, with improved oxygenation and reduced reactive oxygen …
advanced tissue constructs, with improved oxygenation and reduced reactive oxygen …
Physically-based simulation of elastic-plastic fusion of 3D bioprinted spheroids
Spheroids are microtissues containing cells organized in a spherical shape whose diameter
is usually less than a millimetre. Depending on the properties of the environment they are …
is usually less than a millimetre. Depending on the properties of the environment they are …
3D in vitro modelling of post-partum cardiovascular health reveals unique characteristics and signatures following hypertensive disorders in pregnancy
CL Chung Ming, D Pienaar, S Ghorbanpour… - Biology of Sex …, 2024 - Springer
Background Hypertensive disorders of pregnancy (HDP) affect 2–8% of pregnancies and
are associated postpartum with increased cardiovascular disease (CVD) risk, although …
are associated postpartum with increased cardiovascular disease (CVD) risk, although …
Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids
L Zhang, Y Jiang, W Jia, W Le, J Liu, P Zhang… - Cell …, 2024 - Wiley Online Library
Current therapeutic drug exploring targeting at myocardial ischemia/reperfusion (I/R) injury
is limited due to the lack of humanized cardiac models that resemble myocardial damage …
is limited due to the lack of humanized cardiac models that resemble myocardial damage …
Advances in the design, generation, and application of tissue-engineered myocardial equivalents
G Bernava, L Iop - Frontiers in Bioengineering and Biotechnology, 2023 - frontiersin.org
Due to the limited regenerative ability of cardiomyocytes, the disabling irreversible condition
of myocardial failure can only be treated with conservative and temporary therapeutic …
of myocardial failure can only be treated with conservative and temporary therapeutic …