The prevalence of type 2 diabetes is associated with inflammatory bowels diseases,
nonalcoholic steatohepatitis and even a spectrum of cancer such as colon cancer and liver …

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

Renal tubulointerstitial fibrosis was a crucial pathological feature of diabetic nephropathy
(DN), and renal tubular injury might associate with abnormal mitophagy. In this study, we …

Renal tubular damage plays a key role in the pathogenesis of diabetic kidney disease
(DKD), and one of the main pathological process associated with DKD in diabetic mice is the …

Previous studies have shown that mitochondrial dysfunction plays an important role in high-
glucose (HG)-induced podocyte injury and thus contributes to the progression of diabetic …

Apigenin is a flavonoid with antioxidant, anti-inflammatory, and anti-apoptotic activity. In this
study, the potential effects of apigenin on cardiometabolic diseases were investigated in vivo …

Diabetes mellitus (DM) is a chronic metabolic disease caused by a complex interaction of
genetic and environmental factors and is characterized by persistent hyperglycemia. Long …

Diabetic retinopathy (DR) is a serious blinding complication of diabetes. At present, the
therapeutic intervention effect is limited. We aimed to investigate the circRNA expression …

Skeletal muscle is one of the largest organs in the body and the largest protein repository.
Mitochondria are the main energy-producing organelles in cells and play an important role …

Background Diabetic patients are more vulnerable to skeletal complications. Peroxisome
proliferators-activated receptor (PPAR) β/δ has a positive regulatory effect on bone turnover …