LF Dong, J Rohlena, R Zobalova, Z Nahacka… - Journal of Cell …, 2023 - rupress.org
Mammalian genes were long thought to be constrained within somatic cells in most cell types. This concept was challenged recently when cellular organelles including …
T König, H Nolte, MJ Aaltonen, T Tatsuta, M Krols… - Nature cell …, 2021 - nature.com
Mitochondrial-derived vesicles (MDVs) are implicated in diverse physiological processes— for example, mitochondrial quality control—and are linked to various neurodegenerative …
Mitochondria, which are excluded from the secretory pathway, depend on lipid transport proteins for their lipid supply from the ER, where most lipids are synthesized. In yeast, the …
G López‐Doménech, C Covill‐Cooke… - The EMBO …, 2018 - embopress.org
In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTP ases regulate mitochondrial transport along microtubules by linking mitochondria to kinesin and dynein …
Cell division is a complex process with high energy demands. However, how cells regulate the generation of energy required for DNA synthesis and chromosome segregation is not …
Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with other organelles both directly and indirectly. Despite having its own circular genome, the …
AJ Kruppa, F Buss - Journal of cell science, 2021 - journals.biologists.com
Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell …
Mitochondria supply cells with energy in the form of ATP, guide apoptosis, and contribute to calcium buffering and reactive oxygen species production. To support these diverse …
Eukaryotic cells are densely packed with macromolecular complexes and intertwining organelles, continually transported and reshaped. Intriguingly, organelles avoid clashing …