Oxidative stress in obesity: a critical component in human diseases

L Marseglia, S Manti, G D'Angelo, A Nicotera… - International journal of …, 2014 - mdpi.com
Obesity, a social problem worldwide, is characterized by an increase in body weight that
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …

Inflammation, oxidative stress, and obesity

A Fernández-Sánchez, E Madrigal-Santillán… - International journal of …, 2011 - mdpi.com
Obesity is a chronic disease of multifactorial origin and can be defined as an increase in the
accumulation of body fat. Adipose tissue is not only a triglyceride storage organ, but studies …

The medical risks of obesity

X Pi-Sunyer - Postgraduate medicine, 2009 - Taylor & Francis
Obesity is at epidemic proportions in the United States and in other developed and
developing countries. The prevalence of obesity is increasing not only in adults, but …

[HTML][HTML] Non alcoholic fatty liver disease and metabolic syndrome

P Paschos, K Paletas - Hippokratia, 2009 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic entity increasingly
recognized as a major health burden in developed countries. It includes a spectrum of liver …

Betaine chemistry, roles, and potential use in liver disease

CR Day, SA Kempson - Biochimica et Biophysica Acta (BBA)-General …, 2016 - Elsevier
Background Betaine is the trimethyl derivative of glycine and is normally present in human
plasma due to dietary intake and endogenous synthesis in liver and kidney. Betaine is …

Mechanisms of disease progression in nonalcoholic fatty liver disease

J Jou, SS Choi, AM Diehl - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic pathology,
ranging from simple steatosis (also called nonalcoholic fatty liver or NAFL) in its most benign …

Insulin resistance index (HOMA-IR) in the differentiation of patients with non-alcoholic fatty liver disease and healthy individuals

ALFA Salgado, L Carvalho, AC Oliveira… - Arquivos de …, 2010 - SciELO Brasil
CONTEXT: Due to its good correlation to glycemic clamp, HOMA-IR has been widely utilized
as insulin resistance index in clinical and epidemiological studies involving non-alcoholic …

Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO‐1 and AMPK signalling pathways

B Shen, C Zhao, Y Wang, Y Peng… - Journal of cellular …, 2019 - Wiley Online Library
Aucubin (AU) is the main active ingredient of Aucuba japonica which has showed many
positive effects such as anti‐inflammation and liver protection. Non‐alcoholic fatty liver …

[HTML][HTML] Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective

JL Han, HL Lin - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
The incidence of type 2 diabetes (T2DM) is rapidly increasing worldwide. However, the
pathogenesis of T2DM has not yet been well explained. Recent evidence suggests that the …

Imaging-based quantification of hepatic fat: methods and clinical applications

X Ma, NS Holalkere, M Mino-Kenudson, PF Hahn… - Radiographics, 2009 - pubs.rsna.org
Fatty liver disease comprises a spectrum of conditions (simple hepatic steatosis,
steatohepatitis with inflammatory changes, and end-stage liver disease with fibrosis and …