The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

Orf virus is the type species of the Parapoxvirus genus of the family Poxviridae. It induces
acute pustular skin lesions in sheep and goats and is transmissible to humans. The genome …

Orf virus (ORFV) is an important pathogen responsible for a highly contagious zoonotic viral
infection that threatens those who handle sheep and goats. Orf virus is the prototype of the …

Nuclear factor-κB (NF-κB) is an important transcription factor that induces the expression of
antiviral genes and viral genes. NF-κB activation needs the activation of NF-κB upstream …

Orf virus (ORFV) is the etiologic agent of Orf or ecthyma contagiosum in humans but
primarily affects different domestic and wild animals. The disease mostly affects sheep …

Orf virus (ORFV), the prototype species of the Parapoxvirus genus, is an important zoonotic
virus, causing great economic losses in livestock production. At present, there are no …

Summary The IKK/NF‐κ B pathway is an essential signalling process initiated by the cell as
a defence against viral infection like influenza virus. This pathway is therefore a prime target …

Influenza A viruses (IAV-S) belonging to the H1 subtype are endemic in swine worldwide.
Antigenic drift and antigenic shift lead to a substantial antigenic diversity in circulating IAV-S …

Orf virus (ORFV) is a large DNA virus that can harbor and efficiently deliver viral antigens in
swine. Here we used ORFV as a vector platform to deliver chimeric hemagglutinins (HA) of …

African swine fever (ASF) is a hemorrhagic disease of swine characterized by massive
lymphocyte depletion in lymphoid tissues due to the apoptosis of B and T cells, a process …