Current and future perspectives of cell-free DNA in liquid biopsy

S Liu, J Wang - Current Issues in Molecular Biology, 2022 - mdpi.com
A liquid biopsy is a minimally invasive or non-invasive method to analyze a range of tumor
material in blood or other body fluids, including circulating tumor cells (CTCs), cell-free DNA …

Small non-coding RNAs as diagnostic, prognostic and predictive biomarkers of gynecological cancers: an update

MA Diamantopoulos, PG Adamopoulos… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Non-coding RNAs (ncRNAs) comprise a heterogeneous cluster of
RNA molecules. Emerging evidence suggests their involvement in various aspects of …

Correlation between KRAS and NRAS mutational status and clinicopathological features in 414 cases of metastatic colorectal cancer in Morocco: The largest North …

Y Mahdi, M Khmou, A Souadka, HE Agouri… - BMC …, 2023 - Springer
Background Advances in molecular biology have improved understanding of the molecular
features of carcinogenesis and progression of colorectal cancer. It is clear that the efficacy of …

Targeted variant prevalence of FBXW7 gene mutation in colorectal carcinoma propagation. The first systematic review and meta-analysis

HA Afolabi, SM Salleh, Z Zakaria, NM Nafi, AABA Aziz… - Heliyon, 2024 - cell.com
ABSTRACT FBXW7 is a tumour suppressor gene that functions as E3-ubiquitin-ligase,
targeting numerous oncoproteins for degradation, ie, Cyclin-E, c-Myc, and Notch. FBXW7 …

[HTML][HTML] Prognostic role of immunohistochemical PTEN (phosphatase and tensin homolog) expression and PTEN (rs701848) genotypes among Egyptian patients with …

HA Osman, MH Hassan, AM Toema… - Journal of …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most frequent cancer worldwide and the second major
cause of cancer-related death. Thus, we attempted to ascertain the relationship between the …

Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus

ASED Youssef, ARN Zekri, M Mohanad… - Clinical and …, 2023 - Springer
This study aimed to identify BRCA1/2 mutational patterns in the tissue and blood of Egyptian
colorectal cancer (CRC) patients and to study the possible correlation of this mutational …

Somatic Mutations Alter Interleukin Signaling Pathways in Grade II Invasive Breast Cancer Patients: An Egyptian Experience

A Nassar, ARN Zekri, MH Elberry, AM Lymona… - Current Issues in …, 2022 - mdpi.com
This study aimed to investigate the impact of somatic mutations on various interleukin
signaling pathways associated with grade II invasive breast cancer (BC) in Egyptian patients …

New tools for understanding cancer evolution and drug resistance

JL Kallberg - 2022 - theses.hal.science
Colorectal cancer (CRC) is one of the most common cancers and one of the leading causes
of cancer related deaths worldwide. CRC is a heterogeneous disease where there can be …