Safety and pharmaceutical evaluation of a novel natural polymer, ocicum, as solubility and dissolution enhancer in solid dispersion

M Manzoor, SA Raza, MH Asim, NI Bukhari, S Arshad… - Pharmaceuticals, 2022 - mdpi.com
Plant mucilages are commonly employed as excipients in pharmaceutical manufacturing.
Ocimum basilicum (Lamiaceae family), a source of hydrophilic mucilage referred herein as …

Impact of Methods of Preparation on Mechanical Properties, Dissolution Behavior, and Tableting Characteristics of Ibuprofen‐Loaded Amorphous Solid Dispersions

A Uddin, S Halder, N Deb, H Das… - Advances in …, 2024 - Wiley Online Library
This study aims to improve the biopharmaceutical, mechanical, and tableting properties of a
poorly soluble drug, ibuprofen (IBP), by preparing amorphous solid dispersion (ASD) …

Amelioration of tableting properties and dissolution rate of naproxen co-grinded with nicotinamide: Preparation and characterization of co-grinded mixture

N Khizar, N Abbas, M Ahmed, M Ahmad… - Drug Development …, 2024 - Taylor & Francis
Abstract Objective and Significance Reducing the dimensions, when other additives are
present, shows potential as a method to improve the dissolution and solubility of BCS class II …

Surfactant-Assisted Wet Granulation-Based Matrix Tablets without Exceptional Additives: Prolonging Systemic Exposure of Model BCS Class II Ketoprofen

R Shamim, S Shafique, K Hussain, N Abbas, S Ijaz… - AAPS …, 2024 - Springer
The present study was aimed to ameliorate the issue of solubility and thereby, bioavailability
of ketoprofen, a BCS Class II drug. The sustained release matrix tablets (MT) were prepared …