The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Fic. 1. Exon Definition in pre-mRNAs with small exons and large introns. snRNPs (red and
green) and SR protein (yellow) are shown interacting with isolated exons during exon …

Although insects have proven to be valuable models for exploring the function, organization,
and development of the olfactory system, the receptor molecules that bind odors have not …

In Drosophila, enhancer trap strategies allow rapid access to expression patterns, molecular
data, and mutations in trapped genes. However, they do not give any information at the …

Evolution of exon-intron structure of eukaryotic genes has been a matter of long-standing,
intensive debate. The introns-early concept, later rebranded 'introns first'held that protein …

The human genome is revisited using exon and intron distribution profiles. The 26,564
annotated genes in the human genome (build October, 2003) contain 233,785 exons and …

In metazoans, spliceosome assembly is initiated through recognition of the 5′ splice site by
U1 snRNP and the polypyrimidine tract by the U2 small nuclear ribonucleoprotein particle …

Vertebrate synapsins constitute a family of synaptic proteins that participate in the regulation
of neurotransmitter release. Information on the presence of synapsin homologs in …

In higher eukaryotes, the polypyrimidine-tract (Py-tract) adjacent to the 3′ splice site is
recognized by several proteins, including the essential splicing factor U2AF65, the splicing …

Neural specification and differentiation in the Drosophila eye sweep across the unpatterned
epithelial monolayer of the eye imaginal disc following a developmental wave termed the …