We examine theoretical models for circadian oscillations based on transcriptional regulation
in Drosophila and Neurospora. For Drosophila, the molecular model is based on the …

Synthetic biology is a rapidly expanding discipline at the interface between engineering and
biology. Much research in this area has focused on gene regulatory networks that function …

This text is an introduction to dynamical modeling in cell biology. It is not meant as a
complete overview of modeling or of particular models in cell biology. Rather, we use …

In mammals, the circadian pacemaker, which controls daily rhythms, is located in the
suprachiasmatic nucleus (SCN). Circadian oscillations are generated in individual SCN …

Our computational model of the circadian clock comprised the feedback loop between LATE
ELONGATED HYPOCOTYL (LHY), CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and …

Circadian clocks in all organisms include feedback loops that generate rhythmic expression
of key genes. We model the first such loop proposed for the clock of Arabidopsis thaliana …

For 20 years, researchers have thought that circadian clocks are defined by feedback loops
of transcription and translation. The rediscovery of posttranslational circadian oscillators in …

Many organisms display rhythms of physiology and behavior that are entrained to the 24-h
cycle of light and darkness prevailing on Earth. Under constant conditions of illumination …

The suprachiasmatic nucleus governs daily variations of physiology and behavior in
mammals. Within single neurons, interlocked transcriptional/translational feedback loops …

Temperature compensation is a defining feature of circadian oscillators, yet no components
contributing to the phenomenon have been identified in plants. We tested 27 accessions of …