Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021 - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

Microbial foods for improving human and planetary health

LJ Jahn, VM Rekdal, MOA Sommer - Cell, 2023 - cell.com
The current food production system is negatively impacting planetary and human health. A
transition to a sustainable and fair food system is urgently needed. Microorganisms are likely …

Microbial astaxanthin biosynthesis: recent achievements, challenges, and commercialization outlook

C Zhang, X Chen, HP Too - Applied Microbiology and Biotechnology, 2020 - Springer
Astaxanthin is a natural pigment, known for its strong antioxidant activity and numerous
health benefits to human and animals. Its antioxidant activity is known to be substantially …

[HTML][HTML] Current status and applications of adaptive laboratory evolution in industrial microorganisms

SR Lee, P Kim - Journal of Microbiology and Biotechnology, 2020 - ncbi.nlm.nih.gov
Adaptive laboratory evolution (ALE) is an evolutionary engineering approach in artificial
conditions that improves organisms through the imitation of natural evolution. Due to the …

Fruits of their labour: Biotransformation reactions of yeasts during brewery fermentation

N Svedlund, S Evering, B Gibson… - Applied Microbiology and …, 2022 - Springer
There is a growing appreciation for the role that yeast play in biotransformation of flavour
compounds during beverage fermentations. This is particularly the case for brewing due to …

Yeast bioprospecting versus synthetic biology—which is better for innovative beverage fermentation?

L Alperstein, JM Gardner, JF Sundstrom… - Applied microbiology …, 2020 - Springer
Producers often utilise some of the many available yeast species and strains in the making
of fermented alcoholic beverages in order to augment flavours, aromas, acids and textural …

Impact of the genetic improvement of fermenting yeasts on the organoleptic properties of beer

A Astola, E Durán-Guerrero, AB Díaz, C Lasanta… - … Food Research and …, 2023 - Springer
The brewing industry has experienced a significant boom in recent years through the
emergence of, on the one hand, craft breweries that produce beers with unique organoleptic …

Blending wine yeast phenotypes with the aid of CRISPR DNA editing technologies

N van Wyk, H Kroukamp, MI Espinosa… - International journal of …, 2020 - Elsevier
In recent years, CRISPR/Cas9-based genetic editing has become a mainstay in many
laboratories including manipulations done with yeast. We utilized this technique to generate …

Back to the plant: overcoming roadblocks to the microbial production of pharmaceutically important plant natural products

N Ozber, JL Watkins, PJ Facchini - Journal of Industrial …, 2020 - academic.oup.com
Microbial fermentation platforms offer a cost-effective and sustainable alternative to plant
cultivation and chemical synthesis for the production of many plant-derived pharmaceuticals …

You get what you screen for: on the value of fermentation characterization in high-throughput strain improvements in industrial settings

M Wehrs, A de Beaumont-Felt… - Journal of Industrial …, 2020 - academic.oup.com
While design and high-throughput build approaches in biotechnology have increasingly
gained attention over the past decade, approaches to test strain performance in high …