[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

T Shapira, IA Monreal, SP Dion, DW Buchholz… - Nature, 2022 - nature.com
The COVID-19 pandemic caused by the SARS-CoV-2 virus remains a global public health
crisis. Although widespread vaccination campaigns are underway, their efficacy is reduced …

Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8+ T cell responses post SARS-CoV-2 infection

F Gao, V Mallajosyula, PS Arunachalam… - Immunity, 2023 - cell.com
T cells are a critical component of the response to SARS-CoV-2, but their kinetics after
infection and vaccination are insufficiently understood. Using" spheromer" peptide-MHC …

SARS-CoV-2 omicron variant: epidemiological features, biological characteristics, and clinical significance

Y Guo, J Han, Y Zhang, J He, W Yu, X Zhang… - Frontiers in …, 2022 - frontiersin.org
The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

[HTML][HTML] Omicron (B. 1.1. 529) variant of SARS‐CoV‐2: concerns, challenges, and recent updates

RK Mohapatra, R Tiwari, AK Sarangi… - Journal of medical …, 2022 - ncbi.nlm.nih.gov
Omicron (B.1.1.529) variant of SARS‐CoV‐2: Concerns, challenges, and recent updates -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant

M Schubert, F Bertoglio, S Steinke, PA Heine… - BMC medicine, 2022 - Springer
Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In
November 2021, the Omicron variant was discovered and immediately classified as a …

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

L Renia, YS Goh, A Rouers, N Le Bert, WN Chia… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …

Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine

PS Arunachalam, Y Feng, U Ashraf, M Hu… - Science translational …, 2022 - science.org
Despite the remarkable efficacy of COVID-19 vaccines, waning immunity and the
emergence of SARS-CoV-2 variants such as Omicron represents a global health challenge …

Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms

CG Atyeo, LL Shook, S Brigida, RM De Guzman… - Nature …, 2022 - nature.com
The availability of three COVID-19 vaccines in the United States provides an unprecedented
opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact …