This review article addresses the currently available literature on twin screw granulation
(TSG). TSG is an emerging technology rapidly gaining interest in the pharmaceutical …

Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

A comprehensive look at existing technologies and processes for continuous manufacturing
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …

The manufacturing of pharmaceutical dosage forms, which has traditionally been a batch-
wise process, is now also transformed into a series of continuous operations. Some …

Twin screw granulation (TSG) has been reported by different research groups as an
attractive technology for continuous wet granulation. However, in contrast to fluidized bed …

Twin screw granulation (TSG) is increasingly used to produce granules in various industries,
such as food, pharmaceutical, and fine chemicals. However, there is a large parametric …

The present work focuses on the study of the progression of granules in different
compartments along the length of screws in a twin screw granulator (TSG). The effects of …

Twin-screw granulation is a promising continuous alternative for traditional batch high shear
wet granulation (HSWG). The extent of HSWG in a twin screw granulator (TSG) is greatly …

The objective of this work is to present a review of computational tools and models for
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …

The aim of this study was to investigate the process transfer of a commercially available
product from the current batch fluid bed granulation and drying production method to an …