Fracture-related infection

TF Moriarty, WJ Metsemakers, M Morgenstern… - Nature Reviews …, 2022 - nature.com
Musculoskeletal trauma leading to broken and damaged bones and soft tissues can be a life-
threating event. Modern orthopaedic trauma surgery, combined with innovation in medical …

Infection after fracture fixation: current surgical and microbiological concepts

WJ Metsemakers, R Kuehl, TF Moriarty, RG Richards… - Injury, 2018 - Elsevier
One of the most challenging complications in trauma surgery is infection after fracture
fixation (IAFF). IAFF may result in permanent functional loss or even amputation of the …

Prosthetic joint infection

AJ Tande, R Patel - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the
global health care industry. While a small minority of joint arthroplasties will become …

Executive summary: diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America

DR Osmon, EF Berbari, AR Berendt… - Clinical infectious …, 2013 - academic.oup.com
These guidelines are intended for use by infectious disease specialists, orthopedists, and
other healthcare professionals who care for patients with prosthetic joint infection (PJI). They …

[HTML][HTML] Pathogenesis and management of fracture-related infection

M Depypere, M Morgenstern, R Kuehl… - Clinical Microbiology …, 2020 - Elsevier
Background Both fracture-related infections (FRIs) and periprosthetic joint infections (PJIs)
include orthopaedic implant-associated infections. However, key aspects of management …

Biofilm antimicrobial susceptibility testing: where are we and where could we be going?

T Coenye - Clinical microbiology reviews, 2023 - Am Soc Microbiol
Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Hip and knee section, treatment, debridement and retention of implant: proceedings of international consensus on orthopedic infections

JN Argenson, M Arndt, G Babis… - The Journal of …, 2019 - arthroplastyjournal.org
One or more of the authors of this paper have disclosed potential or pertinent conflicts of
interest, which may include receipt of payment, either direct or indirect, institutional support …

[HTML][HTML] The DAIR (debridement, antibiotics and implant retention) procedure for infected total knee replacement–a literature review

SN Qasim, A Swann, R Ashford - SICOT-J, 2017 - ncbi.nlm.nih.gov
Prosthetic joint infection (PJI) is a devastating complication in total knee arthroplasty (TKA)
and third most common cause of revision of TKA with significant morbidity and surgical …

Gram‐negative prosthetic joint infection: outcome of a debridement, antibiotics and implant retention approach. A large multicentre study

D Rodríguez‐Pardo, C Pigrau… - Clinical Microbiology …, 2014 - Wiley Online Library
We aim to evaluate the epidemiology and outcome of gram‐negative prosthetic joint
infection (GN‐PJI) treated with debridement, antibiotics and implant retention (DAIR), identify …

Recommendations for systemic antimicrobial therapy in fracture-related infection: a consensus from an international expert group

M Depypere, R Kuehl, WJ Metsemakers… - … of orthopaedic trauma, 2020 - journals.lww.com
Fracture-related infection (FRI) is a major complication in musculoskeletal trauma and one of
the leading causes of morbidity. Standardization of general treatment strategies for FRI has …