[HTML][HTML] Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

N Singewald, C Schmuckermair, N Whittle… - Pharmacology & …, 2015 - Elsevier
Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

L-Type CaV1.2 Calcium Channels: From In Vitro Findings to In Vivo Function

F Hofmann, V Flockerzi, S Kahl… - Physiological …, 2014 - journals.physiology.org
The L-type Cav1. 2 calcium channel is present throughout the animal kingdom and is
essential for some aspects of CNS function, cardiac and smooth muscle contractility …

[HTML][HTML] From gene to behavior: L-type calcium channel mechanisms underlying neuropsychiatric symptoms

ZD Kabir, A Martínez-Rivera, AM Rajadhyaksha - Neurotherapeutics, 2017 - Elsevier
The L-type calcium channels (LTCCs) Ca v 1.2 and Ca v 1.3, encoded by the CACNA1C
and CACNA1D genes, respectively, are important regulators of calcium influx into cells and …

Hypothesis: the psychedelic ayahuasca heals traumatic memories via a sigma 1 receptor-mediated epigenetic-mnemonic process

A Inserra - Frontiers in pharmacology, 2018 - frontiersin.org
Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and
epigenetic regulation. N, N-Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) …

Brain sites involved in fear memory reconsolidation and extinction of rodents

E Baldi, C Bucherelli - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Fear memory is a motivational system essential for organisms survival having a central role
in organization of defensive behaviors to threat. In the last years there has been a growing …

The role of intracellular calcium stores in synaptic plasticity and memory consolidation

KD Baker, TM Edwards, NS Rickard - Neuroscience & Biobehavioral …, 2013 - Elsevier
Memory processing requires tightly controlled signalling cascades, many of which are
dependent upon intracellular calcium (Ca2+). Despite this, most work investigating calcium …

[HTML][HTML] The evolution of social play in songbirds, parrots and cockatoos-emotional or highly complex cognitive behaviour or both?

G Kaplan - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Social play has been described in many animals. However, much of this social behaviour
among birds, particularly in adults, is still relatively unexplored in terms of the environmental …

L‐type Ca2+ channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes

ZD Kabir, AS Lee… - The Journal of physiology, 2016 - Wiley Online Library
Abstract Brain Cav1. 2 and Cav1. 3 L‐type Ca2+ channels play key physiological roles in
various neuronal processes that contribute to brain function. Genetic studies have recently …

Interaction between genetic variants and exposure to Hurricane Katrina on post-traumatic stress and post-traumatic growth: a prospective analysis of low income …

EC Dunn, N Solovieff, SR Lowe, PJ Gallagher… - Journal of affective …, 2014 - Elsevier
Background There is considerable variation in psychological reactions to natural disasters,
with responses ranging from relatively mild and transitory symptoms to severe and persistent …

Genetic variants associated with resilience in human and animal studies

S Cahill, T Chandola, R Hager - Frontiers in Psychiatry, 2022 - frontiersin.org
Resilience is broadly defined as the ability to maintain or regain functioning in the face of
adversity and is influenced by both environmental and genetic factors. The identification of …