Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

In the retina, hypoxic condition leads to overgrowing leaky vessels resulting in altered
metabolic supply that may cause impaired visual function. Hypoxia-inducible factor-1 (HIF-1) …

Introduction Embryo and fetus grow and mature over the first trimester of pregnancy in a
dynamic hypoxic environment, where placenta development assures an increased oxygen …

Rationale: Mobilization and functions of endothelial progenitor cells (EPCs) are increased in
patients with acute myocardial infarction (AMI). Yet, sleep-disordered breathing (SDB) is …

Hypoxic microenvironment plays an important role in determining stem cell fates. However, it
is controversial to which direction between self‐renewal and differentiation the hypoxia …

The embryo and fetus grow in a hypoxic environment. Intrauterine oxygen levels fluctuate
throughout the pregnancy, allowing the oxygen to modulate apparently contradictory …

Despite the evident progress in neonatal medicine, retinopathy of prematurity (ROP)
remains a serious threat to the vision of premature infants, due to a still partial understanding …

Background Increasing number of evidence shows that soluble factors and extracellular
matrix (ECM) components provide an optimal microenvironment controlling human bone …

Distal arterioles with limited smooth muscles help maintain the high blood flow and low
pressure in the lung circulation. Chronic hypoxia induces lung distal vessel muscularization …

Circulatory vascular diseases, especially those arising from atherosclerosis, are the
predominant cause of mortality and morbidity in the developed world. Current therapies …