Coumarin derivatives are important class of natural plant metabolites that offer variety of
biological activities. They can also be derived synthetically, and a wide variety of synthetic …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …

Considering highly valuable biological and pharmaceutical properties of coumarins, the
synthesis of these heterocycles has been considered for many organic and pharmaceutical …

Benzimidazolium salts (1a and 1b) and respective palladium complexes (2a and 2b) were
prepared and characterized with 1H and 13C NMR, IR, elemental analysis as well as HRMS …

A new series of 7-substituted coumarin scaffolds containing a methyl ester moiety at the C4-
position were synthesized and tested for their in vitro anti-proliferative activity against MCF-7 …

The cancer cases are increasing in fast pace; most of them are resulted from exposure to
harmful pollutants. Genetic factors are responsible for cancer only to a small extent …