Breast cancer (BC) is the most common malignancy in women. It is classified into a few
major molecular subtypes according to hormone and growth factor receptor expression …

Natural as well as synthetic coumarins have recently drawn much attention due to its broad
pharmacological activities. Many coumarins and their derivatives exert anti-coagulant, anti …

Estrogens display intriguing tissue selective action that is of great biomedical importance in
the development of optimal therapeutics for the prevention and treatment of breast cancer …

We have recently demonstrated the existence of a neuromodulatory regulation of prolactin
secretion by the opioid system showing a paradoxical opioid-induced prolactin suppression …

Steroid sulphatase (STS), involved in the hydrolysis of steroid sulphates, plays an important
role in the formation of both active oestrogens and androgens. Since these steroids …

In 1980 sulfamic acid and its N-substituted derivatives were reviewed in Chemical Reviews,
1 effectively updating an earlier 1940 review 2 also in Chemical Reviews. In 1991 the …

Breast cancer is a major cause of death in Western women, with a 10% lifetime risk of the
disease. Most breast cancers are estrogen-dependent. Molecular therapies for breast …

ABSTRACT Introduction: 1, 2, 3, 4-Tetrahydroisoquinoline (THIQ) is one of the 'privileged
scaffolds', commonly found in nature. Initially, this class of compounds was known for its …

Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit
receptor tyrosine kinases, many of which involved in angiogenesis. Response rates vary …

Since its first documentation, breast cancer (BC) has been a conundrum that ails millions of
women every year. This cancer has been well studied by researchers all over the world …