Background: Frailty assessment may inform surgical risk and prognosis not captured by
conventional surgical risk scores. Purpose: To evaluate the evidence for various frailty …

For older people, and in particular frail older people, acute illness and hospitalization are
associated with significant potential harm. One of the major drivers of iatrogenic harm in …

Growth and differentiation factor 11 (GDF11) is a transforming growth factor β superfamily
member with a controversial role in aging processes. We have developed a highly specific …

Study Design. Retrospective study of prospectively collected data. Objective. To determine if
the modified Frailty Index (mFI) could be used to predict postoperative complications in …

Cardiovascular diseases (CVD) affect 60% of people over 60 years of age and are one of
the main causes of death in the world. Diagnosed cardiovascular disease also triples the …

Background Average life expectancy is rising, resulting in increasing numbers of elderly, frail
individuals presenting with coronary artery disease and requiring percutaneous coronary …

Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

Deep neural network models are emerging as an important method in healthcare delivery,
following the recent success in other domains such as image recognition. Due to the …

Background Little is known about the adverse effects of frailty transitions. In this study, we
aimed to characterize the transitions between frailty states and examine their associations …

Study Design. Retrospective cohort study. Objective. The aim of this study was to analyze
postoperative complications and recovery patterns in different modified 11-item frailty index …