Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Single‐cell technologies have revolutionized research in the last decade, including for skin
biology. Single‐cell RNA sequencing has emerged as a powerful tool allowing the …

Cutaneous T cell lymphoma (CTCL) is characterized by the accumulation of malignant T
cells in the skin. However, advanced CTCL pathophysiology remains elusive and …

Granulomatous slack skin (GSS) is an extremely rare subtype of cutaneous T‐cell lymphoma
accompanied by an abundant number of macrophages and is clinically characterized by the …

Inflammatory and immunosuppressive tumor microenvironment (TME) is responsible for
accelerating lymphoma initiation and progression. Graphdiyne oxide (GDYO) nanosheets …

Cancer-associated immune dysfunction is a major challenge for effective therapies. The
emergence of antibodies targeting tumor cell-surface antigens led to advancements in the …

Cutaneous T-cell lymphoma (CTCL) is an uncommon type of lymphoma involving malignant
skin-resident or skin-homing T cells. Canine epitheliotropic lymphoma (EL) is the most …

Background Chemokines are critical players in the local immune responses to tumors.
CCL17 (thymus and activation-regulated chemokine, TARC) and CCL22 (macrophage …

Simple Summary Leukemia is the most common type of childhood malignancy. While the
clinical management of pediatric acute leukemia, especially acute lymphoblastic leukemia …

Detailed analysis of the cells that infiltrate lesional skin cannot be performed in skin biopsy
specimens using immunohistochemistry or cell separation techniques because enzyme …