The binding of programmed death-1 (PD-1) on the surface of T cells and PD-1 ligand 1 (PD-
L1) on tumor cells can prevent the immune-killing effect of T cells on tumor cells and …

Immune checkpoint inhibitors (ICIs), including anti-cytotoxic T-lymphocyte-associated
protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) antibodies, have initiated a new …

Cell migration is crucial for efficient immune responses and is aberrantly used by cancer
cells during metastatic dissemination. Amoeboid migrating cells use myosin II-powered …

Melanoma is a highly aggressive skin cancer, which, although highly immunogenic,
frequently escapes the body's immune defences. Immune checkpoint inhibitors (ICI), such as …

The development of resistance to treatments of melanoma is commonly associated with an
upregulation of the MAPK pathway and the development of an undifferentiated state …

The combination of a PD-L1 inhibitor and an anti-angiogenic agent has become the new
reference standard in the first-line treatment of non-excisable hepatocellular carcinoma …

Melanoma is a serious form of skin cancer that accounts for 80% of skin cancer deaths.
Recent studies have suggested that melanoma invasiveness is attributed to phenotype …

In the pathogenesis of melanoma, NF‐κB is a key signaling pathway. Appling bibliometric
analysis, we identify the frontiers and hotspots about NF‐κB in melanoma, as well as …

Simple Summary Contrary to the conventional understanding of DNA hypermethylation
suppressing gene expression, a new mechanism emerges, suggesting that high methylation …

PURPOSE Patients with stage II and III cutaneous primary melanoma vary considerably in
their risk of melanoma-related death. We explore the ability of methylation profiling to …