Abstract Global Natural Product Social Molecular Networking (GNPS) is an interactive online
small molecule–focused tandem mass spectrometry (MS2) data curation and analysis …

Leishmaniasis (Leishmania species), sleeping sickness (Trypanosoma brucei), and Chagas
disease (Trypanosoma cruzi) are devastating and globally spread diseases caused by …

Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …

Highlights•Trypanosoma cruzi parasites and Chagas disease show specific
tropism.•Metabolism is implicated in T. cruzi parasite tropism and Chagas disease …

Cellular heterogeneity is generally overlooked in infectious diseases. In this study, we
investigated host cell heterogeneity during infection with Trypanosoma cruzi (T. cruzi) …

Chagas disease (CD), caused by Trypanosoma cruzi (T. cruzi) protozoa, is a complicated
parasitic illness with inadequate medical measures for diagnosing infection and monitoring …

Chagas disease (CD) is a parasitic disease caused by Trypanosoma cruzi protozoa,
presenting with cardiomyopathy, megaesophagus, and/or megacolon. To determine the …

Small molecules (less than 1,500 Da) include major biological signals that mediate host-
pathogen-microbiome communication. They also include key intermediates of metabolism …

Chagas disease (CD), caused by the parasite Trypanosoma cruzi, is one of nineteen
neglected tropical diseases. CD is a vector-borne disease transmitted by triatomines, but CD …

Chronic Chagasic cardiomyopathy (CCC) is a Neglected Tropical Disease caused by the
parasite Trypanosoma cruzi. The pathognomonic findings in symptomatic CCC patients and …