Dynamic models of BOLD contrast

RB Buxton - Neuroimage, 2012 - Elsevier
This personal recollection looks at the evolution of ideas about the dynamics of the blood
oxygenation level dependent (BOLD) signal, with an emphasis on the balloon model. From …

Interpreting oxygenation-based neuroimaging signals: the importance and the challenge of understanding brain oxygen metabolism

R Buxton - Frontiers in neuroenergetics, 2010 - frontiersin.org
Functional magnetic resonance imaging (fMRI) is widely used to map patterns of brain
activation based on blood oxygenation level dependent (BOLD) signal changes associated …

Investigating human neurovascular coupling using functional neuroimaging: a critical review of dynamic models

C Huneau, H Benali, H Chabriat - Frontiers in neuroscience, 2015 - frontiersin.org
The mechanisms that link a transient neural activity to the corresponding increase of
cerebral blood flow (CBF) are termed neurovascular coupling (NVC). They are possibly …

A theoretical framework for estimating cerebral oxygen metabolism changes using the calibrated-BOLD method: modeling the effects of blood volume distribution …

VEM Griffeth, RB Buxton - Neuroimage, 2011 - Elsevier
Calibrated blood oxygenation level dependent (BOLD) imaging, a technique used to
measure changes in cerebral O2 metabolism, depends on an accurate model of how the …

Simulation study of brain blood flow regulation by intra-cortical arterioles in an anatomically accurate large human vascular network. Part II: flow variations induced by …

S Lorthois, F Cassot, F Lauwers - Neuroimage, 2011 - Elsevier
In a companion paper (Lorthois et al., Neuroimage, in press), we perform the first simulations
of blood flow in an anatomically accurate large human intra-cortical vascular network …

From in silico astrocyte cell models to neuron-astrocyte network models: A review

F Oschmann, H Berry, K Obermayer, K Lenk - Brain research bulletin, 2018 - Elsevier
The idea that astrocytes may be active partners in synaptic information processing has
recently emerged from abundant experimental reports. Because of their spatial proximity to …

The thermodynamics of thinking: connections between neural activity, energy metabolism and blood flow

RB Buxton - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
Several current functional neuroimaging methods are sensitive to cerebral metabolism and
cerebral blood flow (CBF) rather than the underlying neural activity itself. Empirically, the …

[图书][B] Cerebral blood flow and metabolism: a quantitative approach

SJ Payne - 2018 - World Scientific
The human brain is possibly the most complex organ in existence. This complexity means
that it is capable of great feats, yet has ensured that it remains surprisingly poorly …

Integrated models of neurovascular coupling and BOLD signals: Responses for varying neural activations

EJ Mathias, A Kenny, MJ Plank, T David - NeuroImage, 2018 - Elsevier
A state-of-the-art integrated model of neurovascular coupling (NVC)(Dormanns et al., 2015b;
Dormanns et al., 2016; Kenny et al., 2018) and the BOLD response (Mathias et al., 2017a; …

Connexin and pannexin large-pore channels in microcirculation and neurovascular coupling function

PC Burboa, M Puebla, PS Gaete, WN Durán… - International journal of …, 2022 - mdpi.com
Microcirculation homeostasis depends on several channels permeable to ions and/or small
molecules that facilitate the regulation of the vasomotor tone, hyperpermeability, the blood …