Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Role of exosomes in islet transplantation

J Mattke, S Vasu, CM Darden, K Kumano… - Frontiers in …, 2021 - frontiersin.org
Exosomes are known for their ability to transport nucleic acid, lipid, and protein molecules,
which allows for communication between cells and tissues. The cargo of the exosomes can …

Deciphering pancreatic neuroendocrine tumors: Unveiling through circulating small extracellular vesicles

PK Gorai, S Rastogi, PS Bharti, S Agarwal, S Pal… - Heliyon, 2024 - cell.com
The survival rate over a five-year period for rare pancreatic neuroendocrine tumors
(PanNET) is notably lower compared to other neuroendocrine tumors due to late-stage …

Surface-Bioengineered Extracellular Vesicles Seeking Molecular Biotargets in Lung Cancer Cells

A Kowalczyk, D Dziubak, A Kasprzak… - … Applied Materials & …, 2024 - ACS Publications
Personalized medicine is a new approach to modern oncology. Here, to facilitate the
application of extracellular vesicles (EVs) derived from lung cancer cells as potent advanced …

Sustained high glucose intake accelerates type 1 diabetes in NOD mice

X Li, L Wang, G Meng, X Chen, S Yang… - Frontiers in …, 2022 - frontiersin.org
Introduction Epidemiological studies have suggested that dietary factors, especially high
consumption of high glycaemic index carbohydrates and sugars, may trigger or exacerbate …

Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products

A Stawarska, M Bamburowicz-Klimkowska… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and
therapeutic modalities. This paper describes major GMP-based upstream and downstream …

Exosomes from β-cells promote differentiation of induced pluripotent stem cells into insulin-producing cells through microRNA-dependent mechanisms

Q Guo, Y Lu, Y Huang, Y Guo, S Zhu… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Objective Exosomes have emerged as potential tools for the differentiation of induced
pluripotent stem cells (iPSCs) into insulin-producing cells (IPCs). Exosomal microRNAs are …

Technologies Used for Analysis of Extracellular Vesicle-Omics

X Chen, N Zhu, T Cai, F Yang - Extracellular Vesicles: From Bench to …, 2024 - Springer
Extracellular vesicles (EVs) are naturally occurring and secreted membrane vesicles that
carry proteins, lipids, and RNAs (mRNAs, microRNAs [miRNAs], and long noncoding RNAs …

甲基丙烯酰化明胶/富血小板血浆复合水凝胶构建仿生微环境促进小鼠胰岛瘤细胞MIN6 功能

朱必文, 王东芝, 吴迪, 龚天成, 潘昊鹏, 陆玉华… - 中国组织工程研究, 2023 - cjter.com
甲基丙烯酰化明胶/富血小板血浆复合水凝胶构建仿生微环境促进小鼠胰岛瘤细胞MIN6功能 中国
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Check for updates Methods for the Isolation of Extracellular Vesicles Zimei Chen, Dehua Huo, Xiangsheng Yang, Zhijian Cai, Hua Xiao, and Tong Wang

Z Chen, D Huo - EXTRACELLULAR VESICLES: Basic Research …, 2024 - books.google.com
6.1 Introduction Isolation of purified extracellular vesicles (EVs) is a bottleneck in EV-
associated biological studies and clinical applications. For numerous sample types, the size …