[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022 - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

The bioactivity and applications of pomegranate peel extract: A review

Q Xiang, M Li, J Wen, F Ren, Z Yang… - Journal of Food …, 2022 - Wiley Online Library
Pomegranate peel (PP) is a by‐product in the processing of pomegranate products, which is
usually discarded as a waste. However, a large number of researches have shown that …

Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK pathway: A …

AF AlAsmari, M Alharbi, F Alqahtani, F Alasmari… - Antioxidants, 2021 - mdpi.com
Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

Valproic acid induced liver injury: An insight into molecular toxicological mechanism

D Ezhilarasan, U Mani - Environmental Toxicology and Pharmacology, 2022 - Elsevier
Valproic acid (VPA) is an anti-seizure drug that causes idiosyncratic liver injury. 2-propyl-4-
pentenoic acid (Δ 4 VPA), a metabolite of VPA, has been implicated in VPA-induced …

Progress of research on the role of active ingredients of Citri Reticulatae Pericarpium in liver injury

S Gao, X Chen, Z Yu, R Du, B Chen, Y Wang, X Cai… - Phytomedicine, 2023 - Elsevier
Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

[HTML][HTML] Ellagic acid activates the Keap1-Nrf2-ARE signaling pathway in improving Parkinson's disease: A review

Q Wang, BOA Botchway, Y Zhang, X Liu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Parkinson's disease (PD) is a familiar neurodegenerative disease, accompanied by motor
retardation, static tremor, memory decline and dementia. Heredity, environment, age and …

Role of ellagic acid for the prevention and treatment of liver diseases

V Aishwarya, S Solaipriya… - Phytotherapy …, 2021 - Wiley Online Library
Globally, one of the alarming problems is the prevalence and burden of liver diseases,
which accounts for 2 million cases per year. Chronic liver aetiologies such as hepatitis …

Elucidating the potential side effects of current anti-seizure drugs for epilepsy

E Akyüz, B Köklü, C Ozenen… - Current …, 2021 - benthamdirect.com
Over the decades, various interventions have been developed and utilized to treat epilepsy.
However, the majority of epileptic patients are often first prescribed anti-epileptic drugs …

Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review

A Hosseini, BM Razavi, H Hosseinzadeh - Phytomedicine, 2023 - Elsevier
Background Different chemical toxicants or natural toxins can damage human health
through various routes such as air, water, fruits, foods, and vegetables. Purpose Herbal …