[HTML][HTML] The four epidemiological stages in the global evolution of inflammatory bowel disease

GG Kaplan, JW Windsor - Nature reviews Gastroenterology & …, 2021 - nature.com
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence …

Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

The epidemiology of inflammatory bowel disease: East meets west

WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade
to become a global disease. The increasing number of studies on the incidence and course …

Environmental triggers in IBD: a review of progress and evidence

AN Ananthakrishnan, CN Bernstein… - Nature reviews …, 2018 - nature.com
A number of environmental factors have been associated with the development of IBD.
Alteration of the gut microbiota, or dysbiosis, is closely linked to initiation or progression of …

A comprehensive review and update on Crohn's disease

M Gajendran, P Loganathan, AP Catinella… - Disease-a-month, 2018 - Elsevier
The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Pathomechanisms of oxidative stress in inflammatory bowel disease and potential antioxidant therapies

T Tian, Z Wang, J Zhang - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease whose incidence has
risen worldwide in recent years. Accumulating evidence shows that oxidative stress plays an …

Understanding and preventing the global increase of inflammatory bowel disease

GG Kaplan, SC Ng - Gastroenterology, 2017 - Elsevier
The inflammatory bowel diseases (IBDs) are contemporary conditions of industrialized
societies. The prevalence of IBD continues to increase steadily in Western countries, and …

The global burden of IBD: from 2015 to 2025

GG Kaplan - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Over 1 million residents in the USA and 2.5 million in Europe are estimated to have IBD, with
substantial costs for health care. These estimates do not factor in the'real'price of IBD, which …

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts… - Nature …, 2015 - nature.com
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

Epidemiology and risk factors for IBD

AN Ananthakrishnan - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
IBD, comprising Crohn's disease and ulcerative colitis, is a chronic immunologically
mediated disease at the intersection of complex interactions between genetics, environment …