Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …
mortality worldwide, and its importance is further emphasized in the context of the novel …
Angiotensin-converting enzyme 2 and COVID-19: patients, comorbidities, and therapies
G Pathangey, PP Fadadu… - American Journal of …, 2021 - journals.physiology.org
On March 11, 2020, the World Health Organization declared coronavirus disease 2019
(COVID-19) a pandemic, and the reality of the situation has finally caught up to the …
(COVID-19) a pandemic, and the reality of the situation has finally caught up to the …
Renin–angiotensin–aldosterone system inhibitors and risk of Covid-19
HR Reynolds, S Adhikari, C Pulgarin… - … England Journal of …, 2020 - Mass Medical Soc
Background There is concern about the potential of an increased risk related to medications
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …
A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …
prompted scientists to address an urgent need for defining mechanisms of disease …
AT1 Receptor Blockade Regulates the Local Angiotensin II System in Cerebral Microvessels From Spontaneously Hypertensive Rats
J Zhou, J Pavel, M Macova, ZX Yu, H Imboden, L Ge… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—Blockade of angiotensin II AT1 receptors in cerebral
microvessels protects against brain ischemia and inflammation. In this study, we tried to …
microvessels protects against brain ischemia and inflammation. In this study, we tried to …
ACE2 as a potential therapeutic target for pandemic COVID-19
B Chatterjee, SS Thakur - RSC advances, 2020 - pubs.rsc.org
SARS-CoV-2 virus invades the host through angiotensin-converting enzyme 2 (ACE2)
receptors by decreasing the ACE2 expression of the host. This disturbs the dynamic …
receptors by decreasing the ACE2 expression of the host. This disturbs the dynamic …
Antioxidant and antihypertensive effects of garlic protein and its hydrolysates and the related mechanism
X Gao, Z Xue, Q Ma, Q Guo, L Xing… - Journal of food …, 2020 - Wiley Online Library
Garlic protein (GP) was enzymatically hydrolyzed using pepsin and trypsin followed by the
evaluation of antioxidant and angiotensin‐converting enzyme (ACE) inhibitory activities of …
evaluation of antioxidant and angiotensin‐converting enzyme (ACE) inhibitory activities of …
Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review
Objective To review evidence on routinely prescribed drugs in the UK that could upregulate
or downregulate ACE2 and potentially affect COVID-19 disease. Design Systematic review …
or downregulate ACE2 and potentially affect COVID-19 disease. Design Systematic review …
Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies
H Kai, M Kai, H Niiyama, N Okina, M Sasaki… - Hypertension …, 2021 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) protects against organ damage in
hypertension and cardiovascular diseases by counter regulating the renin-angiotensin …
hypertension and cardiovascular diseases by counter regulating the renin-angiotensin …