Regulatory mechanism of MicroRNA expression in cancer

Z Ali Syeda, SSS Langden, C Munkhzul, M Lee… - International journal of …, 2020 - mdpi.com
Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …

Exosomes of pasteurized milk: potential pathogens of Western diseases

BC Melnik, G Schmitz - Journal of translational medicine, 2019 - Springer
Milk consumption is a hallmark of western diet. According to common believes, milk
consumption has beneficial effects for human health. Pasteurization of cow's milk protects …

The diagnostic and prognostic value of miR-155 in cancers: an updated meta-analysis

Y Wu, Q Hong, F Lu, Z Zhang, J Li, Z Nie… - Molecular Diagnosis & …, 2023 - Springer
Background MicroRNA-155 has been discussed as a biomarker in cancer diagnosis and
prognosis. Although relevant studies have been published, the role of microRNA-155 …

Lifetime impact of cow's milk on overactivation of mTORC1: From fetal to childhood overgrowth, acne, diabetes, cancers, and neurodegeneration

BC Melnik - Biomolecules, 2021 - mdpi.com
The consumption of cow's milk is a part of the basic nutritional habits of Western
industrialized countries. Recent epidemiological studies associate the intake of cow's milk …

Potential pathogenic impact of cow's milk consumption and bovine milk-derived exosomal MicroRNAs in diffuse large B-Cell lymphoma

BC Melnik, R Stadler, R Weiskirchen… - International Journal of …, 2023 - mdpi.com
Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

Circulating RNA biomarkers in diffuse large B-cell lymphoma: a systematic review

P Decruyenaere, F Offner, J Vandesompele - Experimental hematology & …, 2021 - Springer
Diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype of non-
Hodgkin's lymphomas (NHL). DLBCL is an aggressive malignancy that displays a great …

MicroRNA and other non-coding RNAs in Epstein–Barr virus-associated cancers

KI Notarte, S Senanayake, I Macaranas, PM Albano… - Cancers, 2021 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) is associated with a variety of malignancies. In
this review, we discuss EBV-encoded microRNAs and ncRNAs and consider how their …

Research and application of omics and artificial intelligence in cancer

Y Zhang, W Ma, Z Huang, K Liu, Z Feng… - Physics in Medicine …, 2024 - iopscience.iop.org
Cancer has a high incidence and lethality rate, which is a significant threat to human health.
With the development of high-throughput technologies, different types of cancer genomics …

Enhancing RNA inhibitory activity using clamp-G-modified nucleobases

SP Pradeep, V Kumar, S Malik, FJ Slack… - Cell Reports Physical …, 2024 - cell.com
We explore the potential of clamp-G nucleobase-modified peptide nucleic acids (cGPNAs)
as microRNA and messenger RNA inhibitors. For proof of concept, we target miR-155, which …

Circulating miRNAs as biomarkers in aggressive B cell lymphomas

EEE Drees, DM Pegtel - Trends in cancer, 2020 - cell.com
B cell lymphomas are heterogeneous malignancies of hematological origin with vastly
different biology and clinical outcomes. Histopathology of tissue biopsies and image-based …