Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions …

Background In patients with newly diagnosed multiple myeloma, the effect of adding
autologous stem-cell transplantation (ASCT) to triplet therapy (lenalidomide, bortezomib …

Multiple Myeloma (MM) remains an incurable plasma cell neoplasm. Although little is known
about the etiology of MM, several metabolic risk factors such as obesity, diabetes mellitus …

Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

Organ-and body-scale cell atlases have the potential to transform our understanding of
human biology. To capture the variability present in the population, these atlases must …

Cancer outcomes with chemotherapy are inferior in patients of minority racial/ethnic groups
and those with obesity. Chimeric antigen receptor (CAR) T-cell therapy has transformed …

Obesity and obesogenic behaviors are positively associated with both monoclonal
gammopathy of unknown significance (MGUS) and multiple myeloma (MM). As the only …

Prior research establishing that bone interacts in coordination with the bone marrow
microenvironment (BMME) to regulate hematopoietic homeostasis was largely based on …

Multiple myeloma (MM) is twice as common in Black individuals compared with in White
individuals, and diabetes mellitus (DM) disproportionately affects Black patients. Although …

Obesity is associated with an increased risk of developing multiple myeloma (MM). The
molecular mechanisms causing this association is complex and incompletely understood …