Studies of the cell secretome have greatly increased in recent years owing to improvements
in proteomic platforms, mass spectrometry instrumentation and to the increased interaction …

Human infections caused by the opportunist pathogens Burkholderia cepacia complex and
Pseudomonas aeruginosa are of particular concern due to their severity, their multiple …

The genus Burkholderia includes a wide range of Gram-negative bacterial species some of
which are pathogenic to humans and other vertebrates. The most pathogenic species are …

Vaccine research and development are experiencing a renaissance of interest from the
global scientific community. There are four major reasons for this:(1) the lack of efficacious …

The genus Burkholderia consists of diverse species which includes both “friends” and “foes.”
Some of the “friendly” Burkholderia spp. are extensively used in the biotechnological and …

Bacteria build their structures by implementing several macromolecules such as proteins,
polysaccharides, phospholipids, and nucleic acids, which preserve their lives and play an …

Burkholderia cepacia complex (Bcc) is an opportunistic bacterial pathogen that causes
chronic infections in people with cystic fibrosis (CF). It is a highly antibiotic resistant …

Mycoplasma bovis is a risky pathogen mainly responsible for pneumonia and mastitis in
cattle. Up to date, its pathogenesis is not clear. Since secreted proteins have a tricky role in …

The increase in antibiotic resistance and the shortage of new antimicrobials to prevent
difficult bacterial infections underlines the importance of prophylactic therapies to prevent …

Functional genomics has made possible advanced structure-to-function investigation of
pathogens and helped characterize virulence mechanisms. Proteomics has been become a …