DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Homologous recombination (HR) is a highly conserved DNA repair mechanism that protects
cells from exogenous and endogenous DNA damage. Breast cancer 1 (BRCA1) and breast …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Genetic variations along with epigenetic modifications of DNA are involved in colorectal
cancer (CRC) development and progression. CRC is the fourth leading cause of cancer …

Epigenetic disorder mechanisms are one of the causes of cancer. The most important of
these changes is the DNA methylation, which leads to the spread of Helicobacter pylori and …

Cancer cells undergo many different alterations during their transformation, including
genetic and epigenetic events. The controlled division of healthy cells can be impaired …

Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …

Adenomatous polyposis coli (APC) promoter hypermethylation has been frequently
observed in colorectal cancer (CRC). The association between APC promoter methylation …

Worldwide, colorectal cancer (CRC) is one of the most common malignant tumors, leading to
immense social and economic burdens. Currently, the main treatments for CRC include …

This paper reports the preparation of versatile electrochemical biosensing platforms for the
simple, rapid, and PCR-independent detection of the most frequent DNA methylation marks …