Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Commensal fungi in intestinal health and disease

KS Ost, JL Round - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The microbiota is known to influence several facets of mammalian development, digestion
and disease. Most studies of the microbiota have focused on the bacterial component, but …

Bacterial-fungal metabolic interactions within the microbiota and their potential relevance in human health and disease: a short review

A Lapiere, ML Richard - Gut Microbes, 2022 - Taylor & Francis
The composition of the microbiota is the focus of many recent publications describing the
effects of the microbiota on host health. In recent years, research has progressed further …

Local barriers configure systemic communications between the host and microbiota

Q Lu, TS Stappenbeck - Science, 2022 - science.org
Associations between the dynamic community of microbes (the microbiota) and the host they
colonize appear to be vital for ensuring host health. Microbe-host communication is actively …

[HTML][HTML] “Molding” immunity—modulation of mucosal and systemic immunity by the intestinal mycobiome in health and disease

MW Gutierrez, E van Tilburg Bernardes… - Mucosal …, 2022 - Elsevier
Fungi are important yet understudied contributors to the microbial communities of the
gastrointestinal tract. Starting at birth, the intestinal mycobiome undergoes a period of …

The re-emerging role of linoleic acid in paediatric asthma

S Naughten, G Ecklu-Mensah… - European …, 2023 - Eur Respiratory Soc
Asthma is the most common chronic disease within the paediatric population. Although it is
multifactorial, its onset may be linked to early-life exposures with subsequent impact on …

Microbial underdogs: exploring the significance of low-abundance commensals in host-microbe interactions

G Han, S Vaishnava - Experimental & Molecular Medicine, 2023 - nature.com
Our understanding of host-microbe interactions has broadened through numerous studies
over the past decades. However, most investigations primarily focus on the dominant …

Bacterial, fungal, and interkingdom microbiome features of exclusively breastfeeding dyads are associated with infant age, antibiotic exposure, and birth mode

T Heisel, AJ Johnson, S Gonia, A Dillon… - Frontiers in …, 2022 - frontiersin.org
The composition and function of early life gut bacterial communities (microbiomes) have
been proposed to modulate health for the long term. In addition to bacteria, fungi …

Mycobiota–host immune interactions in IBD: coming out of the shadows

ID Iliev - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
2021 has been a productive year for fungal research. Key studies focused on intestinal
inflammation and inflammatory bowel disease highlight antibody-mediated immunity in …

The mycobiome in atopic diseases: inducers and triggers

T Glatthardt, E van Tilburg Bernardes… - Journal of Allergy and …, 2023 - Elsevier
Atopic diseases are characterized by type 2 inflammation, with high allergen-specific T
helper type 2 (Th2) immune responses and elevated immunoglobulin E (IgE) production …