Psoriasis is a chronic inflammatory disease characterised by sharply demarcated
erythematous and scaly skin lesions accompanied by systemic manifestations. Classified by …

IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …

Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Importance Approximately 125 million people worldwide have psoriasis. Patients with
psoriasis experience substantial morbidity and increased rates of inflammatory arthritis …

Immune-mediated inflammatory diseases are common and clinically diverse. Although they
are currently incurable, the therapeutic armamentarium for immune-mediated inflammatory …

Disclosure: Dr. Maitra reports Thrive Earlier Detection has licensed an invention from Johns
Hopkins University in which Dr. Maitra is listed as an inventor. The focus of the license is on …

Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Background There is an unmet need for a treatment for psoriasis that results in complete
skin clearance with a reliably quick response. Bimekizumab is a monoclonal IgG1 antibody …

Atopic dermatitis (AD) is a common yet complex skin disease, posing a therapeutic
challenge with increasingly recognized different phenotypes among variable patient …