Background Implementation research may play an important role in reducing research
waste by identifying strategies that support translation of evidence into practice …

Muscle loss alone, or in the context of sarcopenia or cachexia, is a prevalent condition and a
predictor of negative outcomes in aging and disease. As adequate nutrition is essential for …

Importance Lifestyle interventions in pregnancy optimize gestational weight gain and
improve pregnancy outcomes, with implementation recommended by the US Preventive …

The interest and the rationale for meaningful engagement of patients as partners in clinical
trials of pain treatments has been increasing. No specific guidance on patient engagement …

Distinct from industry and cooperative group clinical trials, investigator-initiated trials (IITs)
are unsolicited trials designed and led by physicians that positively impact current clinical …

There remains wide variation in treatment patterns and outcomes for kidney patients, and
nephrology continues to lag behind other medical specialties in the number and quality of …

Chronic low back pain (CLBP) is a complex multidimensional condition impacting physical
activity, function, quality of life and health. It is common practice for health professionals to …

Clinical trials have significantly evolved over the last century, with rapid advancements in
delivery of electronic or virtually over the last 2 years. Clinical trials have improved the …

Severe traumatic brain injury (TBI) is a global health problem, with an estimated six million
people injured worldwide annually. Over half die or suffer long-term serious disability that …