Tacrine (1) was the first acetylcholinesterase inhibitor (AChEI) introduced in therapy for the
treatment of Alzheimer's disease (AD), but similarly to the most recent approved AChEIs and …

Chaperone-mediated autophagy (CMA) represents a selective form of autophagy involved
in the degradation of specific soluble proteins containing a pentapeptide motif that is …

MicroRNAs (miRNAs) have been shown to have complicated implications in the
pathogenesis of Parkinson's disease (PD). However, the role of miR‐29c and the underlying …

In the recent past, huge emphasis has been given to the epigenetic alterations of the genes
responsible for the cause of neurological disorders. Earlier, the scientists believed somatic …

The underlying molecular pathogenesis in hepatocellular carcinoma remains poorly
understood. The transcription factor MEF2D promotes survival in various cell types and it …

Parkinson's disease (PD) is a common neurological disorder worldwide, characterized by
loss of dopaminergic neurons and decrease of dopamine content. Mitochondria plays an …

The MEF2 (myocyte enhancer factor 2) family of transcription factors is composed of four
distinct vertebrate genes. These factors were first identified in muscle but are also present in …

Mitochondrial dysfunction is the foremost perpetrator of the nigrostriatal dopaminergic
neurodegeneration leading to Parkinson's disease (PD). However, the roles played by …

The degenerative loss through apoptosis of dopaminergic neurons in the substantia nigra
pars compacta plays a primary role in the progression of Parkinson's disease (PD). Our in …

Chrysin, a flavonoid compound existing in several plants, is applied as a dietary supplement
because of its beneficial effects on general human health and alleviation of neurological …