BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications
KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
Time to re‐consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma
G Gandolfi, V Sancisi, S Piana… - International Journal of …, 2015 - Wiley Online Library
The BRAF V600E mutation, resulting from the BRAFT1799A transversion, is the most
common genetic mutation in papillary thyroid carcinoma (PTC), with a mean frequency close …
common genetic mutation in papillary thyroid carcinoma (PTC), with a mean frequency close …
TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease
M Melo, A Gaspar da Rocha, R Batista… - The Journal of …, 2017 - academic.oup.com
Context Little is known about the frequency of key mutations in thyroid cancer metastases
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …
Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma
O Koperek, C Kornauth, D Capper… - The American journal …, 2012 - journals.lww.com
The V600E mutation of the B-type Raf kinase (BRAF) gene is a common event in papillary
thyroid carcinoma (PTC) and seems to play a key role in the development and progression …
thyroid carcinoma (PTC) and seems to play a key role in the development and progression …
Allele Percentage of the BRAF V600E Mutation in Papillary Thyroid Carcinomas and Corresponding Lymph Node Metastases: No Evidence for a Role in Tumor …
G Gandolfi, V Sancisi, F Torricelli… - The Journal of …, 2013 - academic.oup.com
Context: The relevance of the BRAF V600E mutation in papillary thyroid carcinoma (PTC) as
a negative prognostic factor is a subject of intense debate. This mutation has been …
a negative prognostic factor is a subject of intense debate. This mutation has been …
BRAF V600E and lymph node metastases in papillary thyroid cancer
P Chen, L Pan, W Huang, H Feng… - Endocrine …, 2020 - ec.bioscientifica.com
Objective: To evaluate the relationship between the BRAF V600E mutation in lymph node
metastasis (LNM) and its invasive characteristics in papillary thyroid cancer (PTC). Material …
metastasis (LNM) and its invasive characteristics in papillary thyroid cancer (PTC). Material …
A Novel Complex BRAF Mutation Detected in a Solid Variant of Papillary Thyroid Carcinoma
S Chiosea, M Nikiforova, H Zuo, J Ogilvie, M Gandhi… - Endocrine …, 2009 - Springer
BRAF gene mutations are identified in about 45% of papillary thyroid carcinomas (PTC) and
represent the most common genetic event in this tumor. Here, we report a case of PTC, solid …
represent the most common genetic event in this tumor. Here, we report a case of PTC, solid …
[PDF][PDF] Detection of Plasma BRAFV600E Mutation Is Associated with Lung Metastasis in Papillary Thyroid Carcinomas
BH Kim, IJ Kim, BJ Lee, JC Lee, IS Kim… - Yonsei medical …, 2015 - synapse.koreamed.org
Purpose The BRAFV600E mutation represents a novel indicator of the progression and
aggressiveness of papillary thyroid carcinoma (PTC). The purpose of this study was to …
aggressiveness of papillary thyroid carcinoma (PTC). The purpose of this study was to …
The preeminence of growth pattern and invasiveness and the limited influence of BRAF and RAS mutations in the occurrence of papillary thyroid carcinoma lymph …
Prognostic factors indicative of papillary thyroid carcinoma (PTC) aggressive behaviour
remain incompletely established partially due to the different composition of the series on …
remain incompletely established partially due to the different composition of the series on …
Clinicopathological features of rare BRAF mutations in Korean thyroid cancer patients
The most common BRAF mutation in thyroid cancer is c. 1799T> A (p. Val600Glu), and other
BRAF mutations are rarely reported. We investigated the clinicopathological features of …
BRAF mutations are rarely reported. We investigated the clinicopathological features of …