Cancer has become one of the leading causes of morbidity and mortality worldwide. This
disease is classified broadly by tissue, organ, and system; different cancer types and …

Background: Curcumin is a main bioactive constituent of turmeric (Curcuma longa L.) with
pleiotropic health beneficial effects. However, poor bioavailability is the major barrier to the …

Although various research efforts have been made to produce a vascular-like network
structure as scaffolds for tissue engineering, there are still several limitations. Meanwhile, no …

Polyethylenimines (PEIs) are being explored as efficient non-viral nanocarriers for nucleic
acid delivery in vitro and in vivo. To address limitations regarding PEI efficacy and …

Aims Gene therapy is a promising strategy for the treatment of various diseases.
Polyethylenimine (PEI) has received considerable attention for gene delivery applications …

This study aimed to develop novel elastic films based on chitosan and poly (3-hydroxypropyl
ethyleneimine) or P3HPEI for the rapid delivery of haloperidol. P3HPEI was synthesized …

Targeted delivery by polymer-based nanoparticles has been considered as an efficient
approach to transfer genetic materials into cells. Considering the over expression of integrin …

A major hurdle for exploring RNA interference (RNAi) in a therapeutic setting is still the issue
of in vivo delivery of small RNA molecules (siRNAs). The chemical modification of …

This study was carried out to develop a simple and efficient method to isolate DNA directly
from biological samples using iron oxide nanoparticles (IONPs) functionalized with …

The efficiency of gene therapy is often dictated by the gene delivery system. Cationic
polymers are essential elements of gene delivery systems. The relatively cheap cationic …