Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …

Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix
components during tissue development, homeostasis, repair and disease. Despite this …

Smooth muscle cells (SMCs) execute important physiological functions in numerous vital
organ systems, including the vascular, gastrointestinal, respiratory, and urogenital tracts …

Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …

Tendon injuries heal via a scar-mediated response, and there are no biological approaches
to promote more regenerative healing. Mouse flexor tendons heal through the formation of …

Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …

Tendons and ligaments are fibrous connective tissues vital to the transmission of force and
stabilization of the musculoskeletal system. Arising in precise regions of the embryo …

Introduction. Regeneration of fibrochondrocytes is essential for the healing of the tendon‐
bone interface (TBI), which is similar to the formation of neurogenic heterotopic ossification …

The myotendinous junction (MTJ) is a specialized domain of the multinucleated myofibre
that is faced with the challenge of maintaining robust cell–matrix contact with the tendon …

Despite the requirement for Scleraxis-lineage (ScxLin) cells during tendon development, the
function of ScxLin cells during adult tendon repair, post-natal growth, and adult homeostasis …