Identification, discrimination and heterogeneity of fibroblasts

U Lendahl, L Muhl, C Betsholtz - Nature communications, 2022 - nature.com
Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix
components during tissue development, homeostasis, repair and disease. Despite this …

[HTML][HTML] Bidirectional roles of skeletal muscle fibro-adipogenic progenitors in homeostasis and disease

W Chen, W You, TG Valencak, T Shan - Ageing Research Reviews, 2022 - Elsevier
Sarcopenia and myopathies cause progressive muscle weakness and degeneration, which
are closely associated with fat infiltration and fibrosis in muscle. Recently, experimental …

Evolving roles of muscle-resident fibro-adipogenic progenitors in health, regeneration, neuromuscular disorders, and aging

M Theret, FMV Rossi, O Contreras - Frontiers in Physiology, 2021 - frontiersin.org
Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited
neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of …

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

G Giuliani, M Rosina, A Reggio - The FEBS journal, 2022 - Wiley Online Library
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has
contributed to modify the monocentric view of muscle regeneration beyond muscle satellite …

Single-cell RNA sequencing analysis of human bone-marrow-derived mesenchymal stem cells and functional subpopulation identification

Z Xie, W Yu, G Ye, J Li, G Zheng, W Liu, J Lin… - … & Molecular Medicine, 2022 - nature.com
Mesenchymal stem cells (MSCs) are a common kind of multipotent cell in vivo, but their
heterogeneity limits their further applications. To identify MSC subpopulations and clarify …

Single-nucleus and bulk RNA sequencing reveal cellular and transcriptional mechanisms underlying lipid dynamics in high marbled pork

L Wang, X Zhao, S Liu, W You, Y Huang, Y Zhou… - npj Science of …, 2023 - nature.com
Pork is the most consumed meat in the world, and its quality is associated with human
health. Intramuscular fat (IMF) deposition (also called marbling) is a key factor positively …

The role and therapeutic potential of stem cells in skeletal muscle in sarcopenia

Z Cai, D Liu, Y Yang, W Xie, M He, D Yu, Y Wu… - Stem Cell Research & …, 2022 - Springer
Sarcopenia is a common age-related skeletal muscle disorder featuring the loss of muscle
mass and function. In regard to tissue repair in the human body, scientists always consider …

κ-Carrageenan/konjac glucomannan composite hydrogel-based 3D porcine cultured meat production

X Gu, S Hua, Y Huang, S Liu, Y Wang, M Zhou… - Food …, 2024 - Elsevier
Alternative technology for cultured meat production holds the potential to alleviate ethical,
environmental, and public health concerns stemming from conventional husbandry. As a key …

Integrative single-cell RNA-seq and ATAC-seq analysis of myogenic differentiation in pig

S Cai, B Hu, X Wang, T Liu, Z Lin, X Tong, R Xu… - BMC biology, 2023 - Springer
Background Skeletal muscle development is a multistep process whose understanding is
central in a broad range of fields and applications, from the potential medical value to …

The association of lipid metabolism and sarcopenia among older patients: a cross-sectional study

Y Jiang, B Xu, K Zhang, W Zhu, X Lian, Y Xu, Z Chen… - Scientific Reports, 2023 - nature.com
Sarcopenia has become a heavy disease burden among the elderly. Lipid metabolism was
reported to be involved in many degenerative diseases. This study aims to investigate the …